Kavitha Yaddanapudi,


Assistant Professor, Department of Medicine; Associate Scientist, James Graham Brown Cancer Center

Research Program
Molecular Targets

Education
BS, Osmania University, Hyderabad, India, 1994
MS, Madurai Kamaraj University, Madurai, India, 1996
Ph.D., Indian Institute of Science, Bangalore, India, Biochemistry, 2003

Research and Professional Experience

2003 - 2009
Post Doctoral Research Scientist, Center for Infection and Immunity, Mailman School of Public Health, Columbia University, New York, NY

2009 - 2010
Associate Research Scientist, Mailman School of Public Health, Columbia University, New York, NY

2010 - present
Instructor, Department of Medicine and James Graham Brown Cancer Center, University of Louisville, Louisville, KY

Selected Awards and Professional Honors

1994 - 1996
Student Fellowship, Department of Biotechnology, Government of India

1996 - 2002
Junior and Senior Research Fellowship, IISc, Bangalore, India

1996 - 2002
Junior and Senior Research Fellowship, Council of Scientific and Industrial Research, Government of India

2005 - 2007
National Alliance for Research on Schizophrenia and Depression (NARSAD), Young Investigator Award

Publications

Yaddanapudi K, Hornig M, Serge R, Miranda JD, Baghban A, Villar G, Lipkin, WI.  Passive transfer of streptococcus-induced antibodies reproduces behavioral disturbances in a mouse model of pediatric autoimmune neuropsychiatric disorders associated with streptococcal infection (PANDAS). Mol Psychiatry; advance online publication, 11 August 2009 (Nature Publishing Group; DOI 10.1038mp 2009.77)

Miranda JD, Yaddanapudi K, Hornig M, Lipkin WI.  Astrocytes recognize intracellular polyinosinic-polycytidylic acid via MDA-5.  FASEB J 23(4):1064-71, 2008

Abraham S, Yaddanapudi K, Thomas S, Damodaran A, Ramireddy B, Manjunath R.  Nonclassical MHC-I and Japanese encephalitis virus infection: Induction of H-2Q4, H-2T23 and H-2T10. Virus Res 133(2):239–49, 2008

Williams BL, Hornig M, Yaddanapudi K, Lipkin WI.  Hippocampal poly (ADP-Ribose) polymerase 1 and caspase 3 activation in neonatal bornavirus infection.  J Virol 82(4):1748–58, 2008

Kavitha Y, Manjunath R.  Replication of JEV in mouse brain induces alterations in lymphocyte response. Acta Virol 51(3):179–87, 2007

Williams BL, Yaddanapudi K, Hornig M, Lipkin WI.  Spatiotemporal Analysis of Purkinje Cell Degeneration Relative to Parasagittal Expression Domains in a Model of Neonatal Viral Infection.  J Virol 81(6):2675–87, 2007

Yaddanapudi K, Palacios G, Towner JS, Nichol ST, Chen I, Sariol CA, Lipkin WI.  Implication of a retrovirus-like glycoprotein peptide in Ebola virus and 
Marburg virus immunopathogenesis.  FASEB J 20:2519–30, 2006

Williams BL, Yaddanapudi K, Kirk CM, Soman A, Hornig, M, Lipkin I.  Metallothioneins and zinc dysregulation contribute to neurodevelopmental damage in a model of perinatal viral infection.  Brain Pathol 16(1):1–14, 2006

Hoffman KL, Hornig M, Yaddanapudi K, Jabado O, Lipkin WI.  A murine model for neuropsychiatric disorders associated with group A beta-hemolytic streptococcal infection. J Neurosci 24:1780–91, 2004

Kavitha Y, Manjunath R.  Induction of MHC 1 and thymic depletion due to replication of JEV in mouse brain.  Arch Virol 149:2079–93, 2004

Contact Information

CTR Building
505 South Hancock Street
Louisville, KY 40202