Tumor Immunobiology
The overall goal of the Tumor Immunobiology Program is to understand the role of the immune system and inflammation in the development and progression of cancer, and to harness the power of the immune system to develop novel immune-based therapies and vaccines against all types of cancer.
The program has 21 members who come from a wide variety of disciplines ranging from basic immunology to structural biology and molecular imaging. This breadth is a major strength of the program and allows its members to address complex and technically challenging projects. Other strengths of this program include: (i) the strong translational emphasis on immunologic research; (ii) substantive collaborative relationships with the Structural Biology Program, particularly molecular modeling; and (iii) the integration of new faculty members with strong backgrounds in cellular and molecular immunology and tumor immunotherapy into the program.
The objectives of this program have broadened in relationship to the research interests of its members. The original goal – to develop a better understanding of chemokines and chemokine receptors in the biology of cancer – remains important but is now augmented by research in basic and applied tumor immunology and immunotherapy.
Our overall focus is now clustered into two interrelated thematic areas: 1) chemokines and their receptors in tumor development, angiogenesis and metastasis, and 2) tumor immunotherapy and approaches to overcome immune evasion of tumors to generate effective long-term anti-tumor immunity.
At right you will find links to information about Tumor Immunobiology research projects that are currently in progress.
Tumor Immunobiology
The overall goal of the Tumor Immunobiology Program is to understand the role of the immune system and inflammation in the development and progression of cancer, and to harness the power of the immune system to develop novel immune-based therapies and vaccines against all types of cancer.
The program has 21 members who come from a wide variety of disciplines ranging from basic immunology to structural biology and molecular imaging. This breadth is a major strength of the program and allows its members to address complex and technically challenging projects. Other strengths of this program include: (i) the strong translational emphasis on immunologic research; (ii) substantive collaborative relationships with the Structural Biology Program, particularly molecular modeling; and (iii) the integration of new faculty members with strong backgrounds in cellular and molecular immunology and tumor immunotherapy into the program.
The objectives of this program have broadened in relationship to the research interests of its members. The original goal – to develop a better understanding of chemokines and chemokine receptors in the biology of cancer – remains important but is now augmented by research in basic and applied tumor immunology and immunotherapy.
Our overall focus is now clustered into two interrelated thematic areas: 1) chemokines and their receptors in tumor development, angiogenesis and metastasis, and 2) tumor immunotherapy and approaches to overcome immune evasion of tumors to generate effective long-term anti-tumor immunity.
At right you will find links to information about Tumor Immunobiology research projects that are currently in progress.