Keith R. Davis, PhD

Research Program

Research Interests

Education

1980-1985
Graduate Research Assistant, Department of Molecular, Cellular & Developmental Biology, University of Colorado, Boulder

1985-1986      
Postdoctoral Research Associate, Complex Carbohydrate Center, University of Georgia, Athens

1986-1989      
Research Fellow, Department of Molecular Biology, Massachusetts General Hospital, Boston

1986-1989      
Research Fellow, Department of Genetics, Harvard Medical School, Boston

1989-1995      
Assistant Professor, Departments of Plant Biology, Plant Pathology, and Biotechnology Center, Ohio State University, Columbus

1991-1999      
Co-founder and Associate Director, Arabidopsis Biological Resource Center, Ohio State University

1995-1999      
Associate Professor, Depts. of Plant Biology, Plant Pathology, and Plant Biotechnology Center, Ohio State University

1997-1999      
Director, Plant Biotechnology Center, Ohio State University

1999-2000      
Manager, Molecular Biology & Genetics, Plant Research Department, Icoria, Inc. (Formerly Paradigm Genetics, Inc. [ICOR], Research Triangle Park, North Carolina 

1999-2003      
Adjunct Associate Professor, Department of Plant Biology, Ohio State University

2000-2002      
Director, Plant Research Department, Icoria, Inc.

2002-2004      
Adjunct Professor, Department of Botany, North Carolina State University

2002-2006      
Vice President, Agricultural Biotechnology, Icoria, Inc.

2005-2006      
Executive Consultant, Agricultural Biotechnology, Icoria, Inc.

2006-present  
Professor, Department of Pharmacology & Toxicology, University of Louisville, School of Medicine, Louisville, Kentucky

2006-present
Director, Owensboro Cancer Research Program, Owensboro Medical Health System, Owensboro, Kentucky

Selected Awards and Professional Honors

1991-1994
Member, Biochemistry, Physiology & Molecular Biology Committee, The American Phytopathological Society

2000-2002
Steering Committee Member, North Carolina Plant Molecular Biology Consortium

2004-2005
Science and Regulatory Affairs Committee Member, Biotechnology Industry Organization

2004-2005
BTEC Industry Advisory Board, North Carolina State University

2006-present
Board of Directors, Kentucky BioProcessing, LLC, Owensboro, Kentucky

Publications

Davis KR, Schultz TW, Dumont JN. Toxic and teratogenic effects of selected aromatic amines on embryos of the amphibian Xenopus laevis.  Arch Environm Contam Toxicol 10:371-91, 1981

Davis KR, Lyon GD, Darvill AG, Albersheim P. Host-pathogen interactions XXV. Endopolygalacturonic acid lyase form Erwinia carotovora elicits phytoalexin accumulation by releasing plant cell wall fragments.  Plant Physiol 74:52-60, 1984

Davis KR, Darvill AG, Albersheim P, Dell A. Host-pathogen interactions XXIX. Oligogalacturonides released from sodium polypectate by endopolygalacturonic acid lyase are elicitors of phytoalexins in soybean.  Plant Physiol 80:568-77, 1986

Davis KR, Darvill AG, Albersheim P, Dell A. Host-pathogen interactions XXX. Characterizations of elicitors of phytoalexin accumulation in soybean released from soybean cell walls by endopolygalacturonic acid lyase.  Z Naturforschung 41c:39-48, 1986

Davis KR, Darvill AG, Albersheim P. Host-pathogen interactions XXXI. Several biotic and abiotic elicitors act synergistically in the induction of phytoalexin accumulation in soybean.  Plant Mol Biol 6:23-32, 1986

Davis KR, Hahlbrock K. Induction of defense responses in cultured parsley cells by plant cell wall fragments.  Plant Physiol 85:1286-90, 1987

Davis KR, Ausubel FM. Characterization of elicitor-induced defense responses in suspension-cultured cells of Arabidopsis.  Mol Plant Microbe Interact 2:363-8, 1989

Dong X, Mindrinos M, Davis KR, Ausubel FM. Induction of Arabidopsis thaliana defense genes by virulent and avirulent Pseudomonas syringae strains and by a cloned avirulence gene.  The Plant Cell 3:61-71, 1991

Davis KR, Schott E, Ausubel FM. Virulence of selected phytopathogenic pseudomonads in Arabidopsis thaliana.  Mol Plant Microbe Interact 4:477-88, 1991

Stenger DC, Davis KR, Bisaro DM. Limited replication of tomato golden mosaic virus DNA in explants of non-host species.  Mol Plant Microbe Interact 5:525-7, 1992

Melan MA, Dong X, Endara ME, Davis KR, Ausubel FM, Peterman TK. An Arabidopsis thaliana lipoxygenase gene is induced by pathogens, abscisic acid and methyl jasmonate.  Plant Physiol 101:441-50, 1993

Wanner LA, Mittal S, Davis KR. Recognition of the avirulence gene avrB from Pseudomonas syringae pv. glycinea by Arabidopsis thaliana.  Mol Plant Microbe Interact 6:582-91, 1993

Stenger DC, Davis KR, Bisaro DM. Recombinant beet curly top virus genomes exhibit both parental and novel pathogenic phenotypes.  Virology 200:677-85, 1994

Sharma YK, Davis KR. Ozone-induced expression of stress-related genes in Arabidopsis thaliana.  Plant Physiol 105:1089-96, 1994

Lee S, Stenger DC, Bisaro DM, Davis KR. Identification of Ioci in Arabidopsis that confer resistance to geminivirus infection.  Plant J 6:525-35, 1994

Wanner LA, Li G, Ware D, Somssich IE, Davis KR. The phenylalanine ammonia-lyase gene family in Arabidopsis thaliana.  Plant Mol Biol 27:327-38, 1995

Mittal S, Davis KR. Role of the phytotoxin coronatine in the infection of Arabidopsis thaliana by Pseudomonas syringae pv. tomato.  Mol Plant Microbe Interact 8:165-71, 1995

Lee D, Ellard M, Wanner LA, Davis KR, Douglas CJ. The Arabidopsis thaliana 4-coumarate: CoAligase (4CL) gene: stress and developmentally regulated expression and nucleotide sequence of its cDNA.  Plant Mol Biol 28:871-84, 1995

Sharma YK, Davis KR. Isolation of a novel ozone-induced cDNA in Arabidopsis by differential display.  Plant Mol Biol 29:91-8, 1995

Sharma YK, Léon J, Raskin I, Davis KR. Ozone-induced responses in Arabidopsis thaliana: the role of salicylic acid in the accumulation of defense-related transcripts and induced resistance.  Proc Natl Acad Sci USA 93:5099-5104, 1996

Richards KD, Schott EJ, Sharma YK, Davis KR, Gardner RC. Aluminum induces oxidative stress genes in Arabidopsis thaliana.  Plant Physiol 116:409-18, 1998

Zhang W, Han DY, Dick WA, Davis KR, Hoitink HAJ. Compost and compost water extract-induced systemic acquired resistance in cucumber and Arabidopsis.  Phytopathology 88:450-5, 1998

Li H, Lin Y, Wu G, Ware D, Davis KR, Yang Z. Arabidopsis Rho-related GTPases: Differential gene expression in pollen and polar localization in fission yeast.  Plant Physiol 118:407-17, 1998

Koch JR, Scherzer AJ, Eshita SM, Davis KR. Ozone sensitivity in hybrid poplar is correlated with a lack of defense gene activation.  Plant Physiol 118:1243-52, 1998

Rao M, Davis KR. Ozone-induced lesion formation occurs via two distinct mechanisms in Arabidopsis: the role of salicylic acid.  Plant J 17(6):603-14, 1999

Coello P, Sassen A, Haywood V, Davis KR, Walker JC. Biochemical characterization and expression of RLK4, a receptor-like kinase from Arabidopsis thaliana.  Plant Sci 142:83-92, 1999

Koch JR, Creelman RA, Eshita SM, Seskar M, Mullet J, Davis KR. Ozone sensitivity in hybrid poplar correlates with insensitivity to both salicylic acid and jasmonic acid: the role of programmed cell death in lesion formation.  Plant Physiol 123:1-10, 2000

Rao MV, Lee H, Creelman RA, Mullet JE, Davis KR. Jasmonic acid signaling modulates ozone-induced hypersensitive cell death.  Plant Cell 12:1633-46, 2000

Boyes DC, Zayed AM, Ascenzi R, McCaskill AJ, Hoffman NE, Davis KR, Gorlach J. Growth stage-based phenotypic analysis of Arabidopsis: a model for high throughput functional genomics in plants.  Plant Cell 13:1499-1510, 2001

Lee S, Sharma Y, Lee TK, Chang M, Davis KR. Lignification induced by Pseudomonads harboring avirulent genes in Arabidopsis.  Mol Cell 12:25-31, 2001

Rao MV, Lee HI, Davis KR. Ozone-induced ethylene production is dependent on salicylic acid, and both salicylic acid and ethylene act in concert to regulate ozone-induced cell death.  Plant J 32(4):447-56, 2002

Ullah H, Chen JC, Temple B, Boyes DC, Alonso JM, Davis KR, Ecker JR, Jones AM. The ß-subunit of the Arabidopsis G protein negatively regulates auxin-induced cell division and affects multiple developmental processes.  Plant Cell 15:393-409, 2003

Park J, Hwang H, Shim H, Im K, Auh CK, Lee S, Davis KR. Altered cell shapes, hyperplasia, and secondary growth in Arabidopsis caused by beet curly top geminivirus infection.  Mol Cell 17:117-24, 2004