Wayne S. Zundel, PhD

Research and Professional Experience
1994-1996
Research Assistant, Vollum Institute, Oregon Health Sciences University, Portland, OR.

1996-2000
Lecturer/Teaching Assistant, Cancer Biology Program & Radiation Oncology Department, Stanford University, Stanford, CA.

2000-present
Instructor, American Association for Cancer Research (AACR) Molecular Biology in Clinical Oncology Workshop.

2001-2004
Assistant Professor, Department of Radiation Oncology, University of Colorado Health Sciences Center, Denver, CO.

2001-2004
Adjunct Professor, Department of Pulmonary Sciences, University of Colorado Health Science Center, Denver, CO.

2001-2004
Assistant Professor, Division of Medical Oncology, University of Colorado Health Science Center, Denver, CO.

2002-present
Scientific Reviewer: 2002 Dept. of Defense Breast Cancer Research Program. [Molecular Biology and Genetics 1 (MBG-1) panel]

2004-present
Assistant Professor, Department of Radiation Oncology, University of Louisville Health Science Campus, Louisville, KY

2004-present
Member, James Graham Brown Cancer Center, University of Louisville, Louisville, KY

Selected Awards and Professional Honors
1989
Indian Health Service Outstanding Service Award

1991-1992
American Indian Science and Engineering Society Scholarship

1992-1993
Energy Laboratories Scholarship

1993
ASMSU Undergraduate Research Grant

1993-1994
Cobb Foundation Scholarship

1996
Ford Foundation Predoctoral Fellowship

1997-2000
Lucille P. Markey Frontiers in Molecular Medicine Fellowship

2001
Pfizer Atorvastatin Research Award

2003
Pfizer Atorvastatin Research Award

Zundel W, Giaccia A.  Inhibition of the anti-apoptotic PI(3)K/Akt/Bad pathway by stress.  Genes Dev 12:1941-6, 1998

Zundel W, Swiersz LM, Giaccia A.  Caveolin-1 mediated regulation of receptor tyrosine kinase-associated PI(3)K activity by ceramide.  Mol Cell Biol 20:1507-14, 2000.

Zundel W, Schindler C, Koong A, Haas-Kogan D, Kaper F, Chen E, Shalev N, Ryan HE, Johnson RS, Jefferson AB, Stokoe D, Giaccia A.   PTEN controls angiogenic and glycolytic gene expression by hypoxia and growth factors. Genes Dev 14:341-8, 2000.

Zundel W, Schindler C, Haas-Kogan D, Koong A, Kaper F, Chen E, Gottschalk AR, Ryan HE, Johnson RS, Jefferson AB, Stokoe D, Giaccia AJ.  Loss of PTEN facilitates HIF-1-mediated gene expression.  Genes Dev 14:391-6, 2000.

Bemis L, Chan DA, Finkielstein CV, Qi L, Sutphin PD, Chen X, Stenmark K, Giaccia AJ, Zundel W.  Distinct aerobic and hypoxic mechanisms of HIF-alpha regulation by CSN5.  Genes Dev 18(7):739-44, 2004.

Raben D, Helfrich B, Chan DC, Caputo R, Bianco C, Ciadiello F, Zhao T, Franklin W, Baron AE, Zang C, Zundel W, Bunn PA Jr.  The in vitro and in vivo effects of an anti-epidermal growth factor receptor monoclonal antibody (Cetuximab, C225) alone and in combination with radiation and/or chemotherapy in lung cancer.  Clinical Cancer Research, in press.